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Systematic Reviews: A Comprehensive Overview Video Series

Developing a Systematic Review Question and Outcomes

Learning objectives:

  • Discuss how to develop a systematic review question
  • Discuss factors to consider when determining endpoints

After viewing the tutorial, take the quiz to gauge your understanding. (Show Quiz)

References: (Show References)

Master H, Bley JA, Coronado RA, Robinette PE, White DK, Pennings JS, Archer KR. Effects of physical activity interventions using wearables to improve objectively-measured and patient-reported outcomes in adults following orthopaedic surgical procedures: A systematic review. PLoS One. 2022 Feb 15;17(2):e0263562. doi: 10.1371/journal.pone.0263562. PMID: 35167599; PMCID: PMC8846530.

Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA; PRISMA-P Group. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015 Jan 1;4(1):1. doi: 10.1186/2046-4053-4-1. PMID: 25554246; PMCID: PMC4320440.

Pieper D, Rombey T. Where to prospectively register a systematic review. Syst Rev. 2022 Jan 8;11(1):8. doi: 10.1186/s13643-021-01877-1. PMID: 34998432; PMCID: PMC8742923.

Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA; PRISMA-P Group. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015 Jan 2;350:g7647. doi: 10.1136/bmj.g7647. Erratum in: BMJ. 2016 Jul 21;354:i4086. PMID: 25555855.

Tawfik GM, Dila KAS, Mohamed MYF, Tam DNH, Kien ND, Ahmed AM, Huy NT. A step by step guide for conducting a systematic review and meta-analysis with simulation data. Trop Med Health. 2019 Aug 1;47:46. doi: 10.1186/s41182-019-0165-6. PMID: 31388330. PMCID: PMC6670166.

Thomas J, Kneale D, McKenzie JE, Brennan SE, Bhaumik S. Chapter 2: Determining the scope of the review and the questions it will address. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA,editors. Cochrane Handbook for Systematic Reviews of Interventions version 6.4 [Internet]. Cochrane; 2023 [updated 2023 Aug; cited 2023 Oct 18]. Available from: https://training.cochrane.org/handbook.




This video series should be cited as:
Kusnoor SV, Williams AM, Koonce TY, Krump P, Harding L, Zhao J, Giuse NB. Systematic Reviews: A Comprehensive Overview Video Series. Vanderbilt University Medical Center, Center for Knowledge Management, 2023. Available from: https://spi-hub.app.vumc.org/sysrev/home.

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A PDF of the training slides is available here.

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Last updated: October 27, 2023

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