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Vanderbilt University Medical Center
Systematic Reviews: A Comprehensive Overview Video Series
Risk of Bias Assessment
Learning objectives:
- Describe factors that may impact study quality
- Discuss tools for assessing risk of bias
Boutron I, Page MJ, Higgins JPT, Altman DG, Lundh A, Hróbjartsson A. Chapter 7: Considering bias and conflicts of interest among the included studies. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA, editors. Cochrane Handbook for Systematic Reviews of Interventions version 6.4 [Internet]. Cochrane; 2023 [updated 2023 Aug; cited 2023 Oct 18]. Available from: https://training.cochrane.org/handbook.
Institute of Medicine (US) Committee on Standards for Systematic Reviews of Comparative Effectiveness Research. Finding What Works in Health Care: Standards for Systematic Reviews. Eden J, Levit L, Berg A, Morton S, editors. Washington (DC): National Academies Press (US); 2011. PMID: 24983062.
Ma LL, Wang YY, Yang ZH, Huang D, Weng H, Zeng XT. Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better? Mil Med Res. 2020 Feb 29;7(1):7. doi: 10.1186/s40779-020-00238-8. PMID: 32111253; PMCID: PMC7049186.
Popovic A, Huecker MR. Study Bias. 2023 Jun 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan. PMID: 34662027.
Viswanathan M, Ansari MT, Berkman ND, Chang S, Hartling L, McPheeters M, Santaguida PL, Shamliyan T, Singh K, Tsertsvadze A, Treadwell JR. Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions. 2012 Mar 8. In: Methods Guide for Effectiveness and Comparative Effectiveness Reviews [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2008–. PMID: 22479713.
Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, Leeflang MM, Sterne JA, Bossuyt PM; QUADAS-2 Group. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011 Oct 18;155(8):529-36. doi: 10.7326/0003-4819-155-8-201110180-00009. PMID: 22007046.
This video series should be cited as:
Kusnoor SV, Williams AM, Koonce TY, Krump P, Harding L, Zhao J, Giuse NB. Systematic Reviews: A Comprehensive Overview Video Series. Vanderbilt University Medical Center, Center for Knowledge Management, 2023. Available from: https://spi-hub.app.vumc.org/sysrev/home.